Those digital photo frames that are becoming popular hold more than pictures. Millions of them apparently come pre-loaded with a potent virus designed to thwart computer anti-virus programs. The virus is spread from the frame to a computer when the frame is plugged into a USB port.
The virus is difficult to remove, and the article recommends plugging a suspect picture frame into a Linux or Macintosh first to see what is stored in the frame memory (and then deleting it).